疱疹样皮炎中的胃部病变。
Gastric lesion in dermatitis herpetiformis.
作者信息
O'Donoghue D P, Lancaster-Smith M, Johnson G D, Kumar P J
出版信息
Gut. 1976 Mar;17(3):185-8. doi: 10.1136/gut.17.3.185.
Abstract
Five of 33 patients with dermatitis herpetiformis (DH) were found to have gastric parietal cell antibody in their sera, whereas it was not found in 30 healthy controls of comparable age distribution. Fifteen of the patients with DH underwent further studies to investigate the histological and functional state of their gastric mucosa. Atrophic gastritis was found in all five patients whose sera contained gastric parietal cell antibody and in three of 11 patients with no antibody in their sera. In addition, there was marked impairment of acid secretion in the DH group as a whole, but, apart from one patient with overt pernicious anaemia (PA), there was no evidence of malabsorption of B12.
摘要
在33例疱疹样皮炎（DH）患者中，有5例血清中发现胃壁细胞抗体，而在30名年龄分布相当的健康对照者中未发现该抗体。15例DH患者接受了进一步检查，以研究其胃黏膜的组织学和功能状态。血清中含有胃壁细胞抗体的所有5例患者以及血清中无抗体的11例患者中的3例均发现有萎缩性胃炎。此外，整个DH组的胃酸分泌明显受损，但除1例明显的恶性贫血（PA）患者外，没有证据表明存在维生素B12吸收不良。
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