Tandon O P, Manchanda S K
Indian J Physiol Pharmacol. 1976 Jan-Mar;20(1):1-8.
Multiple Unit Activity (MUA) of the hypothalamic arcuate nucleus as indicated by discriminated spikes with window setting between 18-30 uV, the integrated MUA and the cortical EEG of the urethane anaesthetized rats on the proestrous day was recorded with the help of a polygraph. Infusion of LH-RH in the 3rd ventricle markedly increased the arcuate nucleus MUA. The effect started within minutes of infusion, peak came after 20-30 minutes and the activity remained increased for 3-4 hours. Saline infusion in the 3rd ventricle was ineffective. Feedback action of CSF-LH-RH to the arcuate nucleus for the regulation of LH-RH is suggested.
在动情前期，借助多导生理记录仪记录了经氨基甲酸乙酯麻醉的大鼠下丘脑弓状核的多单位活动（MUA），其通过在18 - 30微伏的窗口设置下区分的尖峰表示，同时记录了整合的MUA和皮质脑电图。向第三脑室注入促黄体激素释放激素（LH - RH）显著增加了弓状核的MUA。该效应在注入后几分钟内开始，20 - 30分钟后达到峰值，并且活动持续增加3 - 4小时。向第三脑室注入生理盐水无效。提示脑脊液中的LH - RH对弓状核有反馈作用以调节LH - RH。
