Czosnyka M, Whitehouse H, Smielewski P, Kirkpatrick P, Guazzo E P, Pickard J D
MRC Cambridge Centre for Brain Repair & Academic Neurosurgical Unit, Addenbrooke's Hospital, UK.
Int J Clin Monit Comput. 1994 Nov;11(4):223-32. doi: 10.1007/BF01139874.
Multimodal monitoring in neuro-intensive care requires computer supported data analysis and archiving. This paper describes a computer system that is able to integrate the results of analysis of intracranial pressure, cerebral perfusion pressure, transcranial Doppler blood flow velocity, jugular bulb oxygen saturation, laser Doppler blood flow, near infrared spectroscopy. A research-oriented software installed in a standard IBM PC equipped with a low-cost analog-to-digital converter allows a broad spectrum of waveform analyses, from calculation of simple mean values to a selective waveform detection and cross-correlation analysis. The architecture for the signal processing algorithm, the principles of system interfacing and data presentation are discussed briefly. Results from two years of multimodal monitoring in neuro-intensive care show that, apart from simple recording of time trends of monitored variables, certain calculated parameters are particularly useful in the continuous assessment of cerebral haemodynamic and compensatory reserves. Such parameters include: transcranial Doppler pulsatility indices, the dependence between blood flow velocity or laser Doppler flux and cerebral perfusion pressure and the correlation coefficient between pulse amplitude and mean intracranial pressure.
神经重症监护中的多模态监测需要计算机支持的数据分析和存档。本文描述了一种计算机系统，它能够整合颅内压、脑灌注压、经颅多普勒血流速度、颈静脉球血氧饱和度、激光多普勒血流、近红外光谱分析的结果。安装在配备低成本模数转换器的标准IBM个人电脑中的面向研究的软件允许进行广泛的波形分析，从简单平均值的计算到选择性波形检测和互相关分析。简要讨论了信号处理算法的架构、系统接口和数据呈现的原理。神经重症监护中两年多模态监测的结果表明，除了简单记录监测变量的时间趋势外，某些计算参数在连续评估脑血流动力学和代偿储备方面特别有用。这些参数包括：经颅多普勒搏动指数、血流速度或激光多普勒通量与脑灌注压之间的相关性以及脉冲幅度与平均颅内压之间的相关系数。
