Rescorla F J, Plumley D A, Sherman S, Scherer L R, West K W, Grosfeld J L
Department of Surgery, Indiana University School of Medicine, Indianapolis, USA.
J Pediatr Surg. 1995 Feb;30(2):336-40. doi: 10.1016/0022-3468(95)90585-5.
Recognition of pancreatic injuries is frequently delayed, and optimal treatment is often controversial. The use of endoscopic retrograde cholangiopancreatography (ERCP) has allowed accurate delineation of pancreatic ductal injuries; however, the small size of children and the concern with inducing pancreatitis and/or lesser sac contamination have limited its use in children. In 1988, the authors began using ERCP for selected pancreatic injuries. This report describes their experience with this technique and examines the role of ERCP in pediatric pancreatic injuries. Six children with pancreatic transections resulting from blunt trauma were treated between 1988 and 1993. The age range was 2 1/2 to 8 years, and the weight range was 13.6 to 27.9 kg. The average period from injury to referral to the hospital was 14 days (range, 2 to 30 days). All six children presented with chemical evidence of pancreatitis and had an initial computed tomography (CT) scan; five scans were interpreted as being normal. Five of the six patients had subsequent CT scans, which showed lesser-sac fluid collection. Three patients were treated with drainage (2 percutaneous, 1 open [outside hospital]), and when this failed, ERCP was performed, at 13.6 days (average) after presentation. These three patients underwent ERCP relatively early in the course (an average of 3 days after presentation). All six children had major ductal transections documented through ERCP. After ERCP, the serum amylase level remained elevated in three, increased in one, and normal in one. (It was not measured in one of the recent cases taken for immediate operation.)(ABSTRACT TRUNCATED AT 250 WORDS)
胰腺损伤的诊断常常延迟,最佳治疗方案也往往存在争议。内镜逆行胰胆管造影术(ERCP)的应用使得能够准确描绘胰腺导管损伤情况;然而,儿童体型较小以及对引发胰腺炎和/或小网膜腔污染的担忧限制了其在儿童中的应用。1988年,作者开始将ERCP用于特定的胰腺损伤。本报告描述了他们使用该技术的经验,并探讨了ERCP在小儿胰腺损伤中的作用。1988年至1993年间,对6例因钝性外伤导致胰腺横断伤的儿童进行了治疗。年龄范围为2.5至8岁,体重范围为13.6至27.9千克。从受伤到转诊至医院的平均时间为14天(范围为2至30天)。所有6名儿童均有胰腺炎的化学证据,并进行了初次计算机断层扫描(CT);其中5次扫描结果被判定为正常。6例患者中有5例随后进行了CT扫描,显示小网膜腔有积液。3例患者接受了引流治疗(2例经皮引流,1例在院外进行开放引流),引流失败后,在就诊后13.6天(平均)进行了ERCP。这3例患者在病程中相对较早地接受了ERCP(平均在就诊后3天)。通过ERCP证实所有6名儿童均有主胰管横断。ERCP术后,3例患者血清淀粉酶水平持续升高,1例升高,1例正常。(在近期1例立即进行手术的病例中未检测血清淀粉酶水平。)(摘要截选至250字)