Langston R H, Pavan-Langston D
Int Ophthalmol Clin. 1975 Winter;15(4):125-40. doi: 10.1097/00004397-197501540-00011.
The outlook for keratoplasty in herpetic keratitis has improved significantly over the past decade. While only two out of three grafts in vascularized and regrafted eyes and in eyes with active disease are clear after two years, in quiet eyes with no significant vascularization, the success rate exceeds 80 percent. The significant factor in the improved results, in both favorable and unfavorable cases, is the improvement in surgical technique, involving the operating microscope, the 10-0 nylon suture, and the increased understanding of the pathophysiology of corneal grafting, which has resulted in more sophisticated postoperative care. In our experience, the routine use of high levels of topical steroids in the immediate postoperative period, followed by a rapid tapering of these medications, has been particularly successful.
在过去十年中，疱疹性角膜炎角膜移植的前景有了显著改善。虽然血管化且再次移植的眼睛以及患有活动性疾病的眼睛中，三分之二的移植片在两年后才会清晰，但在没有明显血管化的安静眼睛中，成功率超过80%。在有利和不利的情况下，结果改善的重要因素是手术技术的进步，包括手术显微镜、10-0尼龙缝线的使用，以及对角膜移植病理生理学的进一步理解，这使得术后护理更加精细。根据我们的经验，术后立即常规使用高剂量局部类固醇，随后迅速减少这些药物的用量，这种方法特别成功。
