Ohhira M, Yamada M, Murazumi Y, Ohhira M, Takasugi Y, Namiki M, Suzuki T
Department of Internal Medicine III, Asahikawa Medical College, Hokkaido.
Nihon Ronen Igakkai Zasshi. 1995 Jan;32(1):33-8. doi: 10.3143/geriatrics.32.33.
This paper describes ultrasonically-guided infusion of minocycline hydrochloride solution (MINO infusion therapy) in benign nonparasitic cysts of the liver. MINO infusion therapy was performed in 7 large hepatic cysts and successful results were obtained in 6 lesions. The infusion procedure in the initial 4 hepatic cysts a 7 Fr catheter was placed into the cyst and MINO solution was left in the cyst according to the procedure of ethanol infusion therapy. In the most recent 2 cases the cyst was punctured with a 21G needle, washed with physiologic saline and then infused MINO solution without placement of an indwelling drainage tube. This modified procedure is simple and safe and also yields a good therapeutic result. MINO infusion therapy for benign hepatic cyst is very useful and the modified procedure can be performed safely in elderly patients and in patients with several complications.