Kirby T J, Mack M J, Landreneau R J, Rice T W
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, OH 44195, USA.
J Thorac Cardiovasc Surg. 1995 May;109(5):997-1001; discussion 1001-2. doi: 10.1016/S0022-5223(95)70326-8.
Video-assisted thoracic surgery has been adopted by some thoracic surgeons as the preferred approach over thoracotomy for many benign and malignant diseases of the chest. However, little concrete evidence exists to support this technique as the superior approach. This randomized study was carried out to define the advantages of video-assisted lobectomy over muscle-sparing thoracotomy and lobectomy. Sixty-one patients with presumed clinical stage I non-small-cell lung cancer were entered into the study. Each patient was randomized to muscle-sparing thoracotomy and lobectomy or video-assisted lobectomy. Six patients were excluded from the study either because final pathologic results revealed nonmalignant disease (3 patients) or because an attempted video-assisted lobectomy was converted to a thoracotomy. This left 30 patients in the thoracotomy group and 25 patients in the video-assisted group. No significant differences existed between the two groups in operating time, intraoperative blood loss, duration of chest tube drainage, or length of hospital stay. Significantly more postoperative complications occurred in the thoracotomy group (p < 0.5), the majority of which were prolonged air leaks. Return to work time was not an issue because the majority of the patients were either retired or not working at the time of the operation. Only three patients had persistent postthoracotomy pain (thoracotomy, n = 2; video-assisted lobectomy, n = 1). We conclude that video-assisted lobectomy was not associated with a significant decrease in duration of chest tube drainage, length of hospital stay, postthoracotomy pain, or, in this group of patients, a faster recovery time and return to work. Video-assisted lobectomy continues to expose the patient to the risk of a major pulmonary resection being done in an essentially closed chest. These results illustrate the need for critical evaluation of video-assisted thoracic surgery before the procedure is accepted as a superior approach based on presumed and thus far unproved advantages.
电视辅助胸腔镜手术已被一些胸外科医生采用,作为治疗许多胸部良性和恶性疾病的首选方法,优于开胸手术。然而,几乎没有具体证据支持该技术是更优的手术方法。本随机研究旨在确定电视辅助肺叶切除术相对于保留肌肉开胸肺叶切除术的优势。61例临床诊断为I期非小细胞肺癌的患者纳入本研究。每位患者被随机分配接受保留肌肉开胸肺叶切除术或电视辅助肺叶切除术。6例患者被排除在研究之外,其中3例是因为最终病理结果显示为非恶性疾病,另外3例是因为尝试的电视辅助肺叶切除术转为开胸手术。最终开胸手术组有30例患者,电视辅助组有25例患者。两组在手术时间、术中失血量、胸管引流时间或住院时间方面无显著差异。开胸手术组术后并发症明显更多(p < 0.5),其中大多数为持续性漏气。恢复工作时间不是问题,因为大多数患者在手术时已退休或未工作。只有3例患者有持续性开胸术后疼痛(开胸手术组,n = 2;电视辅助肺叶切除术组,n = 1)。我们得出结论,电视辅助肺叶切除术在胸管引流时间、住院时间、开胸术后疼痛方面并无显著减少,在这组患者中也没有更快的恢复时间和更早返回工作岗位。电视辅助肺叶切除术仍使患者面临在基本封闭胸腔内进行大型肺切除术的风险。这些结果表明,在基于假定且尚未得到证实的优势而将该手术方法视为更优方法之前需要进行严格评估。