Phillips K A, Luft H S, Ritchie J L
Department of General Internal Medicine, School of Medicine, University of California, San Francisco 94105, USA.
Med Care. 1995 May;33(5):502-14. doi: 10.1097/00005650-199505000-00005.
The objective of this study was to examine whether hospital volumes of percutaneous transluminal coronary angioplasty (PTCA) are associated with adverse outcomes (coronary artery bypass graft surgery after PTCA and/or in-hospital mortality), post-PTCA length of stay (LOS), and hospital charges. Discharge data for 24,856 patients undergoing PTCA in 1989 from 110 California hospitals were analyzed. Regression analysis was used to adjust patient discharge data for risk factors. Actual and predicted adverse outcomes, LOS, and charges were compared for hospital volume categories (using 95% confidence intervals). Rates of adverse outcomes were significantly higher than expected in low-volume hospitals (< 201 PTCAs) and significantly lower than expected in high-volume hospitals (> 400 PTCAs). The results were similar for LOS and charges, although the results for charges were less conclusive. The associations of volumes and outcomes were generally consistent for both unadjusted and adjusted analyses, for patients with and without principal diagnoses of acute myocardial infarction, and using different methods and functional forms. Given this association between hospital volumes of PTCA and outcomes, future research should assess the underlying causes of this association and whether limiting the use of low-volume facilities would improve outcomes.
本研究的目的是检验经皮腔内冠状动脉成形术(PTCA)的医院手术量是否与不良结局(PTCA术后冠状动脉旁路移植术和/或住院死亡率)、PTCA术后住院时间(LOS)以及医院收费相关。分析了1989年加利福尼亚州110家医院24,856例接受PTCA患者的出院数据。采用回归分析对患者出院数据的风险因素进行校正。比较了不同医院手术量类别(使用95%置信区间)的实际和预测不良结局、LOS及收费情况。低手术量医院(<201例PTCA)的不良结局发生率显著高于预期,高手术量医院(>400例PTCA)的不良结局发生率显著低于预期。LOS和收费情况的结果相似,尽管收费情况的结果不太具有决定性。对于未经校正和校正后的分析、有和无急性心肌梗死主要诊断的患者以及使用不同方法和函数形式,手术量与结局之间的关联总体上是一致的。鉴于PTCA医院手术量与结局之间的这种关联,未来的研究应评估这种关联的潜在原因以及限制低手术量机构的使用是否会改善结局。