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[主要供血动脉近端大动脉血栓形成后大脑动静脉畸形的自发消退:病例报告]

[Spontaneous regression of cerebral arterio-venous malformation following major artery thrombosis proximal to dominant feeders: a case report].

作者信息

Watanabe H, Nakamura H, Matsuo Y, Sakoh M, Kumon Y, Ohta S, Sakaki S

机构信息

Department of Neurosurgery, Juzen General Hospital, Ehime, Japan.

出版信息

No Shinkei Geka. 1995 Apr;23(4):371-6.

PMID:7739780
Abstract

A rare case of spontaneous regression of cerebral arterio-venous malformation (AVM) is reported. A 76-year-old male was admitted to Juzen General Hospital due to generalized convulsion on August 24, 1987. On admission, results of physical and neurological examinations were normal. Plain CT scans showed an iso-density lesion with a slightly high density spot in the left frontal lobe, and enhanced CT scans showed multiple, irregularly tubular enhancements in the lesion. Left carotid angiogram (CAG) demonstrated an arteriovenous malformation (AVM) in the left frontal lobe, which was fed by the left ACA and MCA and drained by the ascending cerebral vein and superficial Sylvian vein. There was also an anterior communicating artery aneurysm. At the patient's request, he was treated conservatively and was discharged without neurological deficit. Though he continued to take anticonvulsants thereafter, he felt weakness or numbness of the right extremities once a year. Five years after the first admission, he developed sudden onset of right hemiparesis, aphasia and consciousness disturbance. On admission, his platelet aggregation function was elevated. At this time, enhanced CT scans did not show any enhanced area in the left frontal lobe where AVM had been found previously. T2-weighted magnetic resonance image showed a mixed intensity area without any flow void phenomenon suggesting thrombosis of the nidus. Left CAG demonstrated occlusion of the A1-A2 junction of the anterior cerebral artery and disappearance of the AVM. He was treated conservatively again, and was discharged without neurological deficit.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

报告了一例罕见的脑动静脉畸形(AVM)自发消退病例。一名76岁男性于1987年8月24日因全身性惊厥入住寿善综合医院。入院时,体格检查和神经系统检查结果均正常。普通CT扫描显示左额叶有一等密度病灶,内有一稍高密度点,增强CT扫描显示病灶内有多个不规则管状强化影。左颈动脉血管造影(CAG)显示左额叶有一动静脉畸形(AVM),由左大脑前动脉和大脑中动脉供血,经大脑上静脉和大脑外侧浅静脉引流。同时还有一个前交通动脉瘤。应患者要求,对其进行了保守治疗,出院时无神经功能缺损。此后,尽管他继续服用抗惊厥药物,但每年仍会感到右肢无力或麻木。首次入院五年后,他突然出现右半身偏瘫、失语和意识障碍。入院时,他的血小板聚集功能升高。此时,增强CT扫描未显示先前发现AVM的左额叶有任何强化区域。T2加权磁共振图像显示一个混合强度区域,无任何提示病灶血栓形成的血流空洞现象。左CAG显示大脑前动脉A1 - A2交界处闭塞,AVM消失。再次对其进行保守治疗,出院时无神经功能缺损。(摘要截取自250字)

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Spontaneous regression of brain arteriovenous malformations--a clinical study and a systematic review of the literature.脑动静脉畸形的自然消退——一项临床研究及文献系统综述
J Neurol. 2004 Nov;251(11):1375-82. doi: 10.1007/s00415-004-0548-3.