Sorochinskiĭ V V, Kurganov B I
Prikl Biokhim Mikrobiol. 1995 Jan-Feb;31(1):27-35.
The mathematical models of amperometric biosensors, with single- or two-substrate reaction occurring in their cover, were developed. A linear two-parametric equation of steady state was suggested for the biosensor detecting the product of single-substrate reaction corresponding to the Michaelis-Menten scheme. The conditions of equation applicability to description of standard biosensor kinetics in the wide range of substrate concentration, diffusion-module values, and permeability coefficients of three-layer-cover components were studied.
建立了电流型生物传感器的数学模型，该模型考虑了其覆盖层中发生的单底物或双底物反应。针对检测符合米氏方程的单底物反应产物的生物传感器，提出了稳态的线性双参数方程。研究了该方程在广泛的底物浓度、扩散模块值和三层覆盖层组分渗透系数范围内用于描述标准生物传感器动力学的适用条件。
