[从照射野中阻挡敏感结构的放射生物学方面]
[The radiobiological aspects in the blocking of sensitive structures from the irradiation field].
作者信息
Dubben H H, Herrmann T
机构信息
Institut für Biophysik und Strahlenbiologie, Universität Hamburg.
出版信息
Strahlenther Onkol. 1995 Apr;171(4):214-7; discussion 218.
BACKGROUND
In some cases the total dose has to be reduced in a section of an irradiation field by means of a transmission block. This can be performed in 2 different ways: 1. A part of the planned fractions is blocked. 2. The dose of each fraction is reduced using a transmission block (transmission < 100%).
METHOD
For both methods the biological tumor and normal tissue doses were calculated using the linear-quadratic model. A clinical case is discussed.
RESULT AND CONCLUSION
With transmission blocks a therapeutic gain can be obtained.
背景
在某些情况下，必须通过透射挡块在照射野的一部分中降低总剂量。这可以通过两种不同的方式进行：1. 计划分割的一部分被遮挡。2. 使用透射挡块（透射率<100%）降低每个分割的剂量。
方法
对于这两种方法，均使用线性二次模型计算生物肿瘤和正常组织剂量。讨论了一个临床病例。
结果与结论
使用透射挡块可获得治疗增益。
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