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[头颈部肿瘤中对侧光子野与电子野匹配时的剂量不均匀性]

[Dosage inhomogeneities in the matching of opposing photon fields and electron fields in head-neck tumors ].

作者信息

Thesen N, Hoevels M, Treuer H

机构信息

Klinik und Poliklinik für Strahlentherapie, Universität zu Köln.

出版信息

Strahlenther Onkol. 1995 Apr;171(4):231-7.

PMID:7740411
Abstract

PURPOSE

Head and neck tumors are often treated by a multiple-field technique, using a combination of opposing photon fields and electron beams in order to stay within the limit of the myelon tolerance dose. Dose inhomogeneities at field margins must be minimalized to avoid an increased rate of local recurrences or late complications.

METHODS

A polystyrene phantom with a base of 12 x 16 cm was used to investigate the optimal conditions of field matching, using 9 MV photon beams and 8 to 10 MeV electron beams. The evaluation was performed by using an automatic video-densitometer and digital image processing. Dose distributions are presented as 3-dimensional plots and as dose profiles in a depth of 1.2 and 2.5 cm.

RESULTS

In the neck region photon and electron fields cannot exceed a field width of 6 to 7 cm. With unmodified electron fields and opposing photon fields with a 5 mm penumbra optimal geometrical matching is achieved by using an overlap of 2 mm referring to the field margins. Related to a reference dose of 100% the dose in 1.2 and 2.5 cm depth varied between 90% and 115%. Geometrical variations at the field margins, using a gap of 3 mm or an overlap of 5 mm, result in a local underdosage of 75 to 80%, respectively an overdosage of 135 to 150% referring to the reference dose. This dose inhomogeneity occurs at a width of 1 cm around the field margins.

CONCLUSIONS

Regarding clinical and physical aspects the matching of unmodified beams seems to have an advantage compared to the matching of fields with broadened penumbras. For the treatment of patients an immobilisation technique and a precise daily set up is required.

摘要

目的

头颈部肿瘤常采用多野技术治疗,通过对向光子野和电子束相结合,以保持在脊髓耐受剂量限值内。必须将野边缘的剂量不均匀性降至最低,以避免局部复发率增加或晚期并发症。

方法

使用一个底面为12×16 cm的聚苯乙烯模体,采用9 MV光子束和8至10 MeV电子束研究野匹配的最佳条件。通过自动视频密度计和数字图像处理进行评估。剂量分布以三维图和1.2 cm及2.5 cm深度处的剂量剖面表示。

结果

在颈部区域,光子野和电子野的宽度不能超过6至7 cm。对于未修正的电子野和半值层为5 mm的对向光子野,通过以野边缘为参照重叠2 mm可实现最佳几何匹配。相对于100%的参考剂量,1.2 cm和2.5 cm深度处的剂量在90%至115%之间变化。在野边缘使用3 mm的间隙或5 mm的重叠的几何变化,分别导致局部剂量不足75%至80%,相对于参考剂量过量135%至150%。这种剂量不均匀性发生在野边缘周围1 cm的宽度范围内。

结论

从临床和物理方面来看,未修正射野的匹配似乎比半值层加宽的射野匹配具有优势。对于患者的治疗,需要一种固定技术和精确的每日摆位。

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