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子痫患者血浆的总自由基捕获能力

The total free radical trapping ability of blood plasma in eclampsia.

作者信息

Jendryczko A, Tomala J

机构信息

Department of Drug Chemistry, Silesian Medical School, Katowice.

出版信息

Zentralbl Gynakol. 1995;117(3):126-9.

PMID:7740845
Abstract

The interaction between various antioxidants may be important in protecting against oxygen toxicity. We studied the total radical trapping capacity of the antioxidants in plasma (TRAP) and compared the TRAP-level in the patients with eclampsia with that in normal pregnant women. The measured and calculated TRAP-level was higher in the control group than in the group with eclampsia. The uric acid, vitamins E and C and sulfide concentrations were lower in the group of women with eclampsia compared with the controls. The central conclusion from this work is that for patients with eclampsia, the plasma concentrations of the essential nutrients: vitamin E, vitamin C, and cysteinerich protein are too low for optimal antioxidant systems activities.

摘要

多种抗氧化剂之间的相互作用对于预防氧中毒可能很重要。我们研究了血浆中抗氧化剂的总自由基捕获能力(TRAP),并比较了子痫患者与正常孕妇的TRAP水平。对照组中测得和计算出的TRAP水平高于子痫组。子痫组女性的尿酸、维生素E和C以及硫化物浓度低于对照组。这项研究的主要结论是,对于子痫患者,必需营养素(维生素E、维生素C和富含半胱氨酸的蛋白质)的血浆浓度过低,无法使抗氧化系统发挥最佳活性。

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