Schroter R C, Hughes G M
Centre for Biological and Medical Systems, Imperial College of Science, Technology and Medicine, London, England.
Acta Biol Hung. 1994;45(1):101-10.
A simple model relating pore passage time (PPT) to the degree of strain of the membrane of a red cell of diameter DC on passing through a pore (diameter Dp) has been developed. The model was tested for a range of mammalian and fish species for which some data was available for more than one pore size. The strain (epsilon) is estimated as (Dc-Dp)/Dc. For small epsilon, less than approximately 0.45, PPT was small but rose rapidly for higher values. The analysis provides a simple basis for choosing appropriate pore sizes, and consequently strain, for comparing mechanical properties of erythrocytes of different species.
已建立一个简单模型，该模型将孔径通过时间（PPT）与直径为DC的红细胞在通过直径为Dp的孔时膜的应变程度相关联。该模型针对一系列哺乳动物和鱼类物种进行了测试，对于这些物种，有多个孔径的一些数据可用。应变（ε）估计为（Dc - Dp）/Dc。对于小的ε，小于约0.45，PPT较小，但对于更高的值会迅速上升。该分析为选择合适的孔径以及相应的应变提供了一个简单的基础，以便比较不同物种红细胞的力学性能。
