Pisharodi L R
Department of Pathology, Wayne State University, Hutzel Hospital, Detroit, Michigan 48201, USA.
Am J Clin Pathol. 1995 May;103(5):603-8. doi: 10.1093/ajcp/103.5.603.
Basal cell adenocarcinoma of salivary gland is a relatively recently described neoplasm. Histopathologic features of these tumors have been published in the literature mainly in the form of case reports. This paper elaborates and describes the diagnostic fine-needle aspiration cytomorphology of two cases of basal cell adenocarcinoma of parotid gland, which, to the author's knowledge, has not been previously reported in the English literature. Fine-needle aspiration specimens in both cases contained cohesive, focally papillary, and filiform groups of neoplastic cells, which were highly reminiscent of basal cell adenoma on low power examination. Higher power, however, revealed significant cytologic atypia and mitotic activity. Differential diagnoses included basal cell adenoma, epithelial rich pleomorphic adenoma, myoepithelial lesions, small cell undifferentiated carcinoma, and metastatic carcinoma among others.
涎腺基底细胞腺癌是一种相对较新描述的肿瘤。这些肿瘤的组织病理学特征主要以病例报告的形式发表在文献中。本文详细阐述并描述了两例腮腺基底细胞腺癌的诊断性细针穿刺细胞形态学，据作者所知，此前英文文献中尚未有过相关报道。两例的细针穿刺标本均含有肿瘤细胞的黏附性、局灶性乳头状和丝状细胞团，低倍镜检查时与基底细胞腺瘤极为相似。然而，高倍镜下显示出明显的细胞异型性和有丝分裂活性。鉴别诊断包括基底细胞腺瘤、上皮丰富型多形性腺瘤、肌上皮病变、小细胞未分化癌以及转移性癌等。
