患腹泻和未患腹泻幼儿体内针对非致病性肠腔或黏膜细菌抗原的小肠黏膜抗体
Small-intestinal mucosal antibodies against antigens of non-pathogenic luminal or mucosal bacteria in young children with and without diarrhoea.
作者信息
Avigad S, Manuel P, Bampoe V, Walker-Smith J A, Shiner M
出版信息
Lancet. 1978 May 27;1(8074):1130-2. doi: 10.1016/s0140-6736(78)90304-5.
PMID:77420
Abstract
Duodenal mucosal antibody against non-pathogenic bacteria, grown either from the luminal juices or the mucosa itself, was demonstrated for the first time in 7 of 8 children with diarrhoea and only 2 of 7 without diarrhoea. Neither group showed significant histological abnormalities on duodenal biopsy. An aetiological relation between the antibody and the persistence of postenteritis diarrhoea is possible.
摘要
首次在8名腹泻儿童中的7名以及7名无腹泻儿童中的2名体内发现了十二指肠黏膜针对非致病性细菌的抗体，这些细菌要么源自肠腔液，要么源自黏膜本身。两组在十二指肠活检中均未显示出明显的组织学异常。抗体与肠炎后腹泻持续存在之间可能存在病因学关联。
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