Infante-Rivard C
Department of Community Health, Hôpital Sainte-Justine, Montréal, Québec, Canada.
Epidemiology. 1995 Mar;6(2):178-80.
Some studies indicate that children born to younger mothers are at higher risk for wheezing or asthma. I conducted a case-control study that included 457 new cases of asthma in 3- and 4-year-old children and an equal number of controls. I found that, in comparison with children of mothers 30 years of age or older, children of mothers age 26-30 years had an adjusted odd ratio (OR) of 1.16 [95% confidence interval (CI) = 0.73-1.85] of developing asthma; children of mothers between 21 and 25 years of age had an OR of 1.25 (95% CI = 0.76-2.07), and those whose mothers were 20 years of age or younger had an OR of 3.48 (95% CI = 1.08-11.22).
一些研究表明,母亲年龄较小所生的孩子患喘息或哮喘的风险更高。我进行了一项病例对照研究,其中包括457例3至4岁儿童的哮喘新病例以及数量相同的对照组。我发现,与母亲年龄在30岁及以上的孩子相比,母亲年龄在26至30岁的孩子患哮喘的校正比值比(OR)为1.16 [95%置信区间(CI)= 0.73 - 1.85];母亲年龄在21至25岁之间的孩子的OR为1.25(95% CI = 0.76 - 2.07),而母亲年龄在20岁及以下的孩子的OR为3.48(95% CI = 1.08 - 11.22)。