Gradoni L, Bryceson A, Desjeux P
Laboratorio di Parassitologia, Istituto Superiore di Sanità, Rome, Italy.
Bull World Health Organ. 1995;73(2):191-7.
Up-to-date information is given on the epidemiological situation of zoonotic visceral leishmaniasis (ZVL) in nine Mediterranean countries, and on drug regimens adopted in the management of ZVL patients in each country. Results of experimental and clinical trials on the efficacy and tolerability of liposomal amphotericin B in laboratory animals and in patients with ZVL are presented, as well as conclusions and recommendations on drug regimens to be used in the treatment of ZVL.
提供了九个地中海国家人畜共患内脏利什曼病(ZVL)的流行病学最新情况,以及各国治疗ZVL患者所采用的药物治疗方案。介绍了脂质体两性霉素B在实验动物和ZVL患者中的疗效和耐受性的实验及临床试验结果,以及治疗ZVL所用药物治疗方案的结论和建议。