Tseng S H, Hsiao W C
Department of Ophthalmology, National Cheng Kung University Hospital, Tainan, Taiwan, R.O.C.
Cornea. 1995 Mar;14(2):161-6.
Nontuberculous Mycobacterium keratitis is characterized by its indolent course and poor response to antibiotic drugs. Between November 1989 and September 1993, 10 eyes diagnosed to have nontuberculous Mycobacterium keratitis underwent therapeutic lamellar keratectomy in conjunction with fortified topical medications. Nine operated eyes (90%) recovered with a shortened course and healed with an inactive scar. Six patients (60%) achieved a visual acuity of 20/40 or better postoperatively. For recalcitrant nontuberculous Mycobacterium keratitis, therapeutic lamellar keratectomy is highly recommendable for patients with intractable paracentral or peripheral ulcer, for uncompliant patients, for patients who cannot tolerate drug-induced ocular toxicity, or when penetrating keratoplasty is to be reserved for late rehabilitation of the eye.
非结核分枝杆菌角膜炎的特点是病程进展缓慢，对抗生素药物反应不佳。在1989年11月至1993年9月期间，10例被诊断为非结核分枝杆菌角膜炎的患者接受了治疗性板层角膜切除术，并联合强化局部用药。9只手术眼（90%）病程缩短，恢复良好，形成无活性瘢痕愈合。6例患者（60%）术后视力达到20/40或更好。对于顽固性非结核分枝杆菌角膜炎，对于难治性旁中央或周边溃疡患者、不配合治疗的患者、无法耐受药物引起的眼部毒性的患者，或者当穿透性角膜移植术留待后期眼部康复时，强烈推荐进行治疗性板层角膜切除术。
