Ossenblok P, Reits D, Spekreijse H
Graduate School Neurosciences Amsterdam, The Netherlands Ophthalmic Research Institute.
Doc Ophthalmol. 1994;88(1):77-88. doi: 10.1007/BF01203704.
The checkerboard-onset evoked potential does not obtain its adult waveform until late puberty. The changing waveform results from the development of the underlying sources originating in distinct areas of the visual cortex. Since the waveform of checkerboard-onset evoked potential also varies with check size, we studied the dependency of the activity of these sources on check size. A dipole source localization procedure yielded the position and orientation of the equivalent dipoles and the constituent components of the pattern-onset evoked potential, each corresponding to one of these dipoles. For every check size used, the checkerboard-onset evoked potential could be described by a summation of the relative amplitudes of these components. Since the relative amplitude versus check size curves showed a different behavior for each source, they provided evidence of functionally distinct cortical generators. The strength of the striate source was especially sensitive to the fine structure of a pattern, whereas the extrastriate sources contributed mainly for coarse pattern elements.
棋盘格起始诱发电位直到青春期后期才获得其成人波形。波形的变化是由起源于视觉皮层不同区域的潜在源的发育引起的。由于棋盘格起始诱发电位的波形也随方格大小而变化，我们研究了这些源的活动对方格大小的依赖性。偶极子源定位程序得出了等效偶极子的位置和方向以及图形起始诱发电位的组成成分，每个成分对应于其中一个偶极子。对于所使用的每个方格大小，棋盘格起始诱发电位都可以通过这些成分的相对振幅之和来描述。由于相对振幅与方格大小的曲线对每个源表现出不同的行为，它们提供了功能上不同的皮层发生器的证据。纹状源的强度对图案的精细结构特别敏感，而纹外源性主要对粗糙的图案元素起作用。
