Ossenblok P, Reits D, Spekreijse H
The Netherlands Ophthalmic Research Institute, Amsterdam-Zuidoost.
Vision Res. 1992 Oct;32(10):1829-35. doi: 10.1016/0042-6989(92)90044-j.
The checkerboard onset Evoked Potential (EP) does not obtain its adult form before puberty. To determine the site of origin of these processes we studied the origin of the checkerboard onset EP in a group of 10 children between the ages of 6 and 16 years. Since the development of the waveform of the pattern onset EP varies with check size we also studied the dependence of these EPs on check size. The child checkerboard onset EPs described in this paper are dominated by a single source. Following an equivalent dipole source localization approach, the position, orientation and variation in strength of the equivalent dipole is estimated. The position and orientation of this dipole indicates an origin in the primary visual cortex (area 17). The variation in strength of the dipole changes from a single positive deflection, specific for children of 8 years and younger, into a negative-positive complex for the children studied between the age of 9 and 16 years. These changes in waveform must be due to changes in the activity pattern of the striate cortex.
棋盘格起始诱发电位（EP）在青春期前不会呈现其成人形式。为了确定这些过程的起源部位，我们对一组10名年龄在6至16岁之间的儿童的棋盘格起始EP的起源进行了研究。由于图形起始EP波形的发育随方格大小而变化，我们还研究了这些EP对方格大小的依赖性。本文所述的儿童棋盘格起始EP由单一来源主导。采用等效偶极子源定位方法，估计等效偶极子的位置、方向和强度变化。该偶极子的位置和方向表明其起源于初级视觉皮层（17区）。偶极子强度的变化从8岁及以下儿童特有的单一正向偏转，变为9至16岁儿童的负-正复合波。波形的这些变化必定归因于纹状皮层活动模式的变化。
