Zeidler H
Division of Rheumatology, Medizinische Hochschule Hannover, Germany.
Eur J Rheumatol Inflamm. 1994;14(1):3-6.
Geriatric rheumatology and the epidemiology of musculoskeletal diseases in elderly persons constitute a new field. Although difficult to estimate, the prevalence rate of disabling joint diseases increases as people age. Osteoarthritis (OA) is the most common type of joint disease in geriatric patients. Symptomatic OA has a much lower prevalence rate than does radiographic OA. However, symptomatic disease is important in that it may motivate a patient to seek medical attention. The prevalence of rheumatoid arthritis (RA) also increases with advancing age. The onset of RA in both large and small joints in patients older than 60 years is more frequent and begins with greater disease activity as compared to patients younger than 60. Moreover, RA runs a more severe course in older than in younger patients. Thus, epidemiologic data suggest that elderly individuals could be major consumers of nonsteroidal anti-inflammatory drugs (NSAIDs) commonly used in the management of musculoskeletal disorders. The prevalence of these disorders increases with advancing age and, coupled with increasing longevity, poses a growing challenge to practicing physicians in their treatment of these patients.
老年风湿病学以及老年人肌肉骨骼疾病的流行病学构成了一个新领域。尽管难以估计,但致残性关节疾病的患病率会随着人们年龄的增长而增加。骨关节炎(OA)是老年患者中最常见的关节疾病类型。有症状的OA患病率远低于影像学OA。然而,有症状的疾病很重要,因为它可能促使患者寻求医疗关注。类风湿关节炎(RA)的患病率也随着年龄的增长而增加。与60岁以下的患者相比,60岁以上患者的大、小关节RA发病更为频繁,且起病时疾病活动度更高。此外,RA在老年患者中比在年轻患者中病情更严重。因此,流行病学数据表明,老年人可能是常用于治疗肌肉骨骼疾病的非甾体抗炎药(NSAIDs)的主要消费群体。这些疾病的患病率随着年龄的增长而增加,再加上寿命延长,给执业医生治疗这些患者带来了越来越大的挑战。