Gottschalk-Sabag S, Weiss D B
Dept. of Pathology and Cytology, Shaare Zedek Medical Center, Jerusalem.
Harefuah. 1995 Mar 1;128(5):265-6, 336.
The mechanism of spermatozoal degeneration in male genital tract obstruction was evaluated. Epididymal fine-needle aspiration was performed in 17 azoospermic men with distal obstruction of the genital tract, but in whom testicular cytology revealed adequate spermatogenesis. From the contents of each puncture, smears with May-Grunwald-Giemsa and Papanicolaou staining were prepared. All indigenous epididymal cytologic types were identified in the smears. In aspirates which contained spermatozoa, large cells with foamy cytoplasm and round or kidney-shaped nuclei were also found. In some of these foam cells heads of mature spermatozoa were engulfed within the cytoplasm. It is suggested that in male genital tract obstruction, the role of the foam cells within the epididymis may be to phagocytize and disintegrate the trapped spermatozoa. The cellular origin of these foam cells is probably the epithelial lining layer of the epididymis itself.
对男性生殖道梗阻时精子变性的机制进行了评估。对17例无精子症且生殖道远端梗阻但睾丸细胞学显示生精功能正常的男性进行了附睾细针穿刺抽吸。从每次穿刺的内容物中制备了用美-格-姬氏染色法和巴氏染色法染色的涂片。在涂片中鉴定出了所有附睾固有的细胞类型。在含有精子的抽吸物中，还发现了具有泡沫状细胞质和圆形或肾形细胞核的大细胞。在其中一些泡沫细胞的细胞质内吞噬有成熟精子的头部。提示在男性生殖道梗阻时，附睾内泡沫细胞的作用可能是吞噬和分解被困的精子。这些泡沫细胞的细胞来源可能是附睾自身的上皮衬里层。
