Stein M, Zalik M, Drumea K, Lachter J, Militianu D, Haim N
Northern Israel Oncology Center, Rambam Medical Center, Haifa, Israel.
Isr J Med Sci. 1995 Feb-Mar;31(2-3):194-6.
Neutropenic colitis, a severe necrotizing enteropathy, is being recognized with increasing frequency as a life-threatening complication of aggressive chemotherapy mainly for lymphoproliferative and hematologic malignancies. It is often under-recognized clinically, despite its potentially lethal outcome. Both medical and surgical approaches to management are possible. We describe a case of neutropenic colitis involving predominantly the transverse colon in a patient successfully treated for limited-disease small cell lung cancer. This is only the second reported case of neutropenic colitis complicating chemotherapy for small cell lung cancer. A brief review of the diagnosis, clinical features, and management is presented.
中性粒细胞减少性结肠炎是一种严重的坏死性肠病，作为侵袭性化疗主要针对淋巴增殖性和血液系统恶性肿瘤的一种危及生命的并发症，其被认识的频率越来越高。尽管其可能导致致命后果，但在临床上往往未得到充分认识。医学和外科治疗方法都是可行的。我们描述了一例主要累及横结肠的中性粒细胞减少性结肠炎病例，该患者成功治疗了局限性小细胞肺癌。这是第二例报道的小细胞肺癌化疗并发中性粒细胞减少性结肠炎的病例。本文对其诊断、临床特征及治疗进行了简要综述。
