Vicente P, Bellmunt J, Ruiz-Marcellan C, García A, Rovirosa A, Solé L A
Sección de Oncología Médica, Universitària Vall d'Hebron, Barcelona.
Med Clin (Barc). 1993 Sep 11;101(7):261-3.
Primary non Hodgkin's lymphoma of the breast (PNHLB) its an unusual presenting form of malignant breast diseases. Its estimated frequency is around 0.05-0.5% of all breast tumors. Three cases of PNHLB are presented. We analyse the characteristics of presenting features and also we discuss the therapeutic and prognostic implications. They can be initially confused with a typical breast carcinoma due to the unspecific clinical findings with the difficulty to obtain a definitive diagnosis based only on cytologic grounds. The therapeutic and prognostic consequences underlines the importance of immunohistochemistry in the diagnosis of PNHLB.
原发性乳腺非霍奇金淋巴瘤（PNHLB）是一种罕见的乳腺恶性疾病表现形式。据估计，其在所有乳腺肿瘤中的发生率约为0.05 - 0.5%。本文报告3例PNHLB病例。我们分析了其临床表现特征，并探讨了治疗及预后意义。由于临床表现不具特异性，仅基于细胞学检查难以获得明确诊断，故其最初可能会与典型乳腺癌相混淆。治疗及预后结果凸显了免疫组化在PNHLB诊断中的重要性。
