Henchey R, Cibula J, Helveston W, Malone J, Gilmore R L
Department of Neurology, College of Medicine, University of Florida, Gainesville 32610, USA.
Neurology. 1995 May;45(5):977-81. doi: 10.1212/wnl.45.5.977.
Hashimoto's encephalopathy (HE) is a steroid-responsive relapsing disorder that frequently presents with seizures and diffuse EEG abnormalities. We report the EEG findings in seven patients with encephalopathy, seizures, or both, associated with elevated antithyroid antibodies. There were several combinations of findings within the same patient and between patients. The EEGs of five patients had generalized slowing or frontal rhythmic slowing; two also had triphasic waves and one had periodic sharp waves. Three had focal left temporal slowing. HE is heterogeneous clinically and electrographically. A high level of suspicion is necessary to establish the diagnosis.
桥本脑病（HE）是一种对类固醇有反应的复发性疾病，常表现为癫痫发作和脑电图弥漫性异常。我们报告了7例患有脑病、癫痫发作或两者兼有的患者的脑电图结果，这些患者抗甲状腺抗体升高。同一患者以及不同患者之间存在多种检查结果组合。5例患者的脑电图有广泛性慢波或额部节律性慢波；2例还有三相波，1例有周期性尖波。3例有左侧颞叶局灶性慢波。HE在临床和脑电图表现上具有异质性。建立诊断需要高度怀疑。
