Zanetti P P, Sorisio V, Baratta V, Amerio G M, Cavanenghi D, Rosa G, Zappa A, Ruscalla L, Piccolini E, Conti P
I Divisione di Chirurgia Generale, USSL n. 68, Regione Piemone, Ospedale Civile, Asti.
Minerva Chir. 1994 Dec;49(12):1263-8.
The authors analyse a series of 5 patients who underwent pulmonary and parietal resection between 1990 and 1993 due to non.microcytoma bronchogenic carcinoma with invasion of the thoracic wall. The patients comprised four men and one woman aged between 45 and 69 years old. Thoracic pain was present in two patients. Pulmonary resection with extrapleural stripping was performed in two patients whereas a block resection from one to five ribs and the corresponding intercostal spaces was performed in the other three patients. The authors' approach is not to perform these operations according to rigid protocols but to adapt them according to the local status of tumour invasion. Therefore to resort to extrapleural resection when there is a free cleavage plane between parietal pleura and rib wall; resection in block of the wall where the carcinoma has infiltrated the endothoracic fascia or deeper. The authors do not report any major complications and record a postoperative mortality rate of 0%. In two cases the thoracic wall was reconstructed using a sheet of Gore-Tex which did not provoke rejection phenomena. Radiotherapy was carried out in cases with positive lymph nodes. The series presented here is too recent to provide significant data regarding survival. However, the only factor seen to influence prognosis in the five patients was the presence or otherwise of lymph node metastasis, irrespective of the histological type and operation performed. The five year survival rate of T3N0M0 patients is in fact similar to that of T2N0M0 patients.(ABSTRACT TRUNCATED AT 250 WORDS)
作者分析了1990年至1993年间因非微细胞型支气管源性癌侵犯胸壁而接受肺和胸壁切除术的5例患者。患者包括4名男性和1名女性,年龄在45至69岁之间。2例患者有胸痛症状。2例患者行胸膜外剥脱肺切除术,另外3例患者行1至5根肋骨及相应肋间间隙的整块切除术。作者的方法不是按照严格的方案进行这些手术,而是根据肿瘤侵犯的局部情况进行调整。因此,当胸膜壁层与肋骨壁之间有游离的剥离平面时,采用胸膜外切除术;对癌已浸润胸内筋膜或更深部位的胸壁进行整块切除。作者未报告任何严重并发症,术后死亡率为0%。2例患者用一片戈尔特斯(Gore-Tex)重建胸壁,未引发排斥反应。对淋巴结阳性的病例进行了放疗。这里介绍的系列病例时间太近,无法提供有关生存的重要数据。然而,在这5例患者中,唯一被认为影响预后的因素是有无淋巴结转移,而与组织学类型和所施行的手术无关。事实上,T3N0M0患者的5年生存率与T2N0M0患者相似。(摘要截选至250词)