Oliaro A, Filosso P L, Casadio C, Ruffini E, Cianci R, Porrello C, Molinatti M, Cavallo A, Pischedda F, Rizzo M
Cattedra di Chirurgia Toracica, Università degli Studi di Torino.
Minerva Chir. 1994 Dec;49(12):1311-6.
The authors report 4 cases of patients with benign fibrous mesothelioma of the pleura, an extremely rare pathology (not more than 500 cases reported to date in the literature), and discuss biological behaviour, diagnosis and surgical treatment. Benign fibrous mesothelioma is generally diagnosed by chance during chest x-ray given that it is paucisymptomatic; diagnostic procedures include thoracic CT (which may be supplemented by transthoracic needle biopsy) and bronchoscopy. Treatment is surgical and consists of exeresis of the neoplasia; prognosis is excellent and cases are reported in the literature of 24-year follow-up without recurrence. Lastly, the authors underline the importance of modern immunohistochemical techniques which help the surgeon to formulate a precise diagnosis and to differentiate benign fibrous mesothelioma.
作者报告了4例胸膜良性纤维性间皮瘤患者，这是一种极为罕见的病理类型（迄今为止文献报道不超过500例），并讨论了其生物学行为、诊断和外科治疗。良性纤维性间皮瘤通常因症状轻微在胸部X光检查时偶然被诊断出来；诊断程序包括胸部CT（可辅以经胸针吸活检）和支气管镜检查。治疗方式为手术，即切除肿瘤；预后良好，文献中有报道24年随访无复发的病例。最后，作者强调了现代免疫组化技术的重要性，其有助于外科医生做出准确诊断并鉴别良性纤维性间皮瘤。
