Lee S Y, Shin D H, Spoor T C, Kim C, McCarty B, Kim D
Kresge Eye Institute, Wayne State University, Detroit, MI 48201, USA.
Ophthalmic Surg. 1995 Jan-Feb;26(1):25-8.
We investigated retinal vascular changes in nine patients undergoing optic nerve sheath decompression for vision-threatening papilledema associated with pseudotumor cerebri. Two major (one superior and one inferior) retinal venous and arterial calibers were measured before and 1.1 +/- 0.1 months, 3.2 +/- 0.2 months, 5.0 +/- 0.2 months, 7.6 +/- 0.2 months, and 13.0 +/- 1.9 months after surgery. The retinal venous caliber decreased significantly, and the decrease progressed until 3.2 months after surgery. The venous caliber in the contralateral unoperated eyes also decreased significantly. The decrease in the venous caliber in the contralateral unoperated eye as well as in the operated eye following the surgery supports the hypothesis that slow filtration is the mechanism of successful optic nerve sheath decompression. Retinal venous caliber measurement, in either the operated eye or the unoperated fellow eye, can be used to quantitatively monitor the status of papilledema associated with pseudotumor cerebri.
我们对9例因与假性脑瘤相关的视力威胁性视乳头水肿而接受视神经鞘减压术的患者的视网膜血管变化进行了研究。在手术前以及术后1.1±0.1个月、3.2±0.2个月、5.0±0.2个月、7.6±0.2个月和13.0±1.9个月测量了两条主要的（一条上支和一条下支）视网膜静脉和动脉管径。视网膜静脉管径显著减小，且这种减小一直持续到术后3.2个月。对侧未手术眼的静脉管径也显著减小。术后对侧未手术眼以及手术眼的静脉管径减小支持了缓慢滤过是视神经鞘减压术成功机制的假说。测量手术眼或未手术的对侧眼的视网膜静脉管径，可用于定量监测与假性脑瘤相关的视乳头水肿状态。
