Vassilopoulou-Sellin R, Woods D, Quintos M T, Needle M, Klein M J
Pediatr Nurs. 1995 Mar-Apr;21(2):149-53.
Height characteristics in 108 children and 52 adults with neurofibromatosis (NF) were analyzed. Fifty percent of the children and 54% of the adults ranked below the 25th percentile for normal age and sex-adjusted height. It can be concluded that children with NF are short and have increased risk of becoming very short adults. Primary care practitioners and specialists working with these children should recognize the possibility of future short stature and initiate measures to prevent or minimize the psychosocial problems that may result. Given the pronounced risk for shortness, it is important to avoid unrealistic adult height predictions (based on parental stature) when counseling short children with the disease.
对108名患有神经纤维瘤病（NF）的儿童和52名成人的身高特征进行了分析。50%的儿童和54%的成人身高低于根据年龄和性别调整后的正常身高的第25百分位数。可以得出结论，患有NF的儿童身材矮小，成年后变得非常矮小的风险增加。为这些儿童提供治疗的初级保健医生和专科医生应认识到未来身材矮小的可能性，并采取措施预防或尽量减少可能由此产生的心理社会问题。鉴于身材矮小的风险显著，在为患有该疾病的矮小儿童提供咨询时，避免做出不切实际的成人身高预测（基于父母身高）非常重要。
