Ousset P J, Démonet J F, Puel M, Cardebat D, Micas M, Albarède J L, Rascol A, Guiraud B
Service de Neurologie, CHU Purpan, Toulouse.
Rev Neurol (Paris). 1994 Jun-Jul;150(6-7):425-9.
The revised French version of the Hierarchic Dementia Scale (HDS) was assessed in 88 DAT patients (30 men, 58 women, mean age: 70, MMS from 0 to 26). The HDS consisted of 20 subtests which covered the entire range of cognitive functions; each subtest was hierarchically organized. This scale has been validated by the authors in 149 control subjects (Démonet et al., 1990). The goals of the present study were to validate this scale in DAT patients in comparison with the MMS scores and to specify the cognitive impairments of our pathologic population. Results showed that the scores on the HDS were highly correlated with the MMS scores (p < .0001). Some subtests of the HDS (memory subtests and mental control) allow good discrimination between mild demented patients and controls (sensibility = 80.8 p. 100, specificity = 96 p. 100). Conversely some subtests allowed a cognitive follow-up of patients for whom the MMS was no longer useful (MMS scores from 0 to 10). In conclusion, it appears that this scale is useful for drawing cognitive profile of DAT patients and to approach the heterogeneity of dementia.
对88例阿尔茨海默病性痴呆(DAT)患者(30名男性,58名女性,平均年龄:70岁,简易精神状态检查表(MMS)评分0至26分)进行了修订后的法语版等级痴呆量表(HDS)评估。HDS由20个分测验组成,涵盖了认知功能的整个范围;每个分测验都是分层组织的。作者已在149名对照受试者中验证了该量表(德莫内等人,1990年)。本研究的目的是与MMS评分相比,在DAT患者中验证该量表,并明确我们病理人群的认知障碍。结果显示,HDS评分与MMS评分高度相关(p <.0001)。HDS的一些分测验(记忆分测验和心理控制)能够很好地区分轻度痴呆患者和对照者(敏感度 = 80.8 / 100,特异度 = 96 / 100)。相反,一些分测验能够对MMS不再适用的患者(MMS评分0至10分)进行认知随访。总之,该量表似乎有助于描绘DAT患者的认知概况,并探讨痴呆的异质性。