Morfeldt L, Torssander J
Division of Infectious Diseases, Karolinska Institute, Danderyd Hospital, Sweden.
Scand J Infect Dis. 1994;26(6):749-52. doi: 10.3109/00365549409008645.
Five patients with HIV-associated Kaposi's sarcoma (epidemic KS) were treated with foscarnet 180 mg/kg/day i.v. for 10 days. Four of them suffered from severe immunodeficiency with CD4 cell counts below 30 x 10(6)/l. Three of the patients went into long-term remission of KS. One patient was free of relapse for 12 months and 2 patients are still in remission after an observation period of 13 and 20 months respectively. The results suggest a possible role of foscarnet in the treatment of epidemic KS.
