Snityns'kyĭ V V, Antoniak H L
Ukr Biokhim Zh (1978). 1994 Sep-Oct;66(5):3-16.
The molecular mechanisms of selenium regulation of biochemical functions in animal and human tissues are presented in review. It is shown, that in spite of high toxicity selenium is an essential nutrient for people and animals. Taking into account deficit of this microelement in fodder it is necessary to use the selenium compounds in rations of domestic animals and poultry. The study of properties and characteristics of selenoproteins is important in discovering selenium role in regulation of cellular growth processes, the protective effect of this element in prevention of toxic action of heavy metals, xenobiotics and bacterial toxins on organism and anticarcinogenic effect of selenium.
本文综述了硒对动物和人体组织生化功能调节的分子机制。研究表明,尽管硒具有高毒性,但它是人和动物必需的营养素。考虑到饲料中这种微量元素的缺乏,在家畜和家禽日粮中使用硒化合物是必要的。研究硒蛋白的性质和特性对于发现硒在调节细胞生长过程中的作用、该元素在预防重金属、外源性物质和细菌毒素对机体的毒性作用方面的保护作用以及硒的抗癌作用具有重要意义。