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犬特应性皮炎:英国北部和南部两个地点皮内皮肤试验阳性的患病率。

Canine atopic disease: the prevalence of positive intradermal skin tests at two sites in the north and south of Great Britain.

作者信息

Sture G H, Halliwell R E, Thoday K L, van den Broek A H, Henfrey J I, Lloyd D H, Mason I S, Ferguson E

机构信息

Department of Veterinary Clinical Studies, Royal (Dick) School of Veterinary Studies, Summerhall, Edinburgh, UK.

出版信息

Vet Immunol Immunopathol. 1995 Feb;44(3-4):293-308. doi: 10.1016/0165-2427(94)05306-d.

DOI:10.1016/0165-2427(94)05306-d
PMID:7747407
Abstract

Results of intradermal skin test responses to the same panel of 53 allergens were compared in 118 dogs with atopic disease presented at two geographical centres, Edinburgh (87 cases) and London (31 cases). The allergens most commonly positive at both centres were human dander and Dermatophagoides farinae, but positive tests to all of the allergens used occurred in at least one case. The mean number of allergens to which positive tests resulted in atopic dogs was 5.126 (Edinburgh) and 5.129 (London). The majority of animals were sensitive to allergens from more than one group. A significantly higher number of positive reactors to house dust allergen was observed at London than at Edinburgh (P < 0.05), while a significantly higher number of positive reactions to grass pollens was detected at Edinburgh than in London (P < 0.05). Sensitivity to Dermatophagoides pteronyssinus, in the absence of sensitivity to D. farinae, was uncommon and therefore both of these mite allergens should be incorporated in intradermal skin testing panels in Great Britain.

摘要

在两个地理区域中心(爱丁堡87例,伦敦31例)就诊的118只患有特应性疾病的犬中,比较了对同一组53种变应原的皮内皮肤试验反应结果。两个中心最常见的阳性变应原是人类皮屑和粉尘螨,但至少有一例对所有使用的变应原检测呈阳性。特应性犬皮内试验呈阳性的变应原平均数量在爱丁堡为5.126,在伦敦为5.129。大多数动物对来自不止一组的变应原敏感。伦敦对屋尘变应原呈阳性反应的动物数量显著高于爱丁堡(P < 0.05),而爱丁堡对草花粉呈阳性反应的数量显著高于伦敦(P < 0.05)。在对粉尘螨不敏感的情况下,对户尘螨敏感的情况并不常见,因此在英国的皮内皮肤试验组中应同时包含这两种螨变应原。

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