Dotterud L K, Kvammen B, Lund E, Falk E S
Department of Dermatology, University of Tromsø, Norway.
Acta Derm Venereol. 1995 Jan;75(1):50-3. doi: 10.2340/00015555755053.
A study of the prevalence of atopic dermatitis among 7-12-year-old children was carried out in a rural community in Northern Norway close to the Russian border. Of the 424 children investigated, 37% had a past and/or present history of atopic dermatitis (cumulative incidence), whereas 23% were classified as having atopic dermatitis by clinical examination (point prevalence). A history of atopic dermatitis during the past year was reported by 26% of the children. Flexural lichenified dermatitis was present in 88%, and 12% of the children had facial and extensor involvement with or without hand dermatitis. Two thirds of the children showed mild and one third moderate symptoms; only 3 children had severe symptoms confirmed by clinical examination. The ratio of girls with atopic dermatitis to boys with atopic dermatitis was about 1.3:1. Onset of atopic dermatitis within the first 2 years of life occurred in 64% of cases, with no sex differences. Remission of atopic dermatitis occurred in 1 of 8 before the age of 5, with earlier cessation in boys. Mucous membrane atopy alone was reported by 13% of them and in combination with atopic dermatitis also in 13%. Parental history of atopic diseases was reported by 37% of all children, more frequently in mothers than in fathers. In families with no parental history of atopic diseases, 41% of the children appeared to develop some kind of atopic disease; this increased to 63% with a single and to 75% with a double parental history.(ABSTRACT TRUNCATED AT 250 WORDS)
在挪威北部靠近俄罗斯边境的一个农村社区,对7至12岁儿童的特应性皮炎患病率进行了一项研究。在接受调查的424名儿童中,37%有特应性皮炎的既往和/或现病史(累积发病率),而通过临床检查,23%被归类为患有特应性皮炎(点患病率)。26%的儿童报告在过去一年有特应性皮炎病史。88%的儿童有屈侧苔藓化性皮炎,12%的儿童面部和伸侧有皮损,伴或不伴有手部皮炎。三分之二的儿童症状较轻,三分之一症状中等;只有3名儿童经临床检查确诊为重度症状。患特应性皮炎的女孩与男孩的比例约为1.3:1。64%的病例在生命的头2年内出现特应性皮炎,无性别差异。8名儿童中有1名在5岁前特应性皮炎缓解,男孩缓解更早。13%的儿童仅报告有黏膜过敏,13%同时伴有特应性皮炎。37%的儿童报告有特应性疾病的家族史,母亲比父亲更常见。在无特应性疾病家族史的家庭中,41%的儿童似乎患了某种特应性疾病;单亲家族史时这一比例增至63%,双亲家族史时则增至75%。(摘要截选于250词)