Svensson A, Vahlquist A
Department of Dermatology, County Hospital, Kristianstad, Sweden.
Acta Derm Venereol. 1995 Jan;75(1):70-1. doi: 10.2340/00015555757071.
We describe a 3-year-old girl with long-standing yellow discoloration of her skin and a 3-fold increase in the plasma carotenoid concentration compared to normal, but no history of excessive carotene intake or familial carotenemia. When put on a carotene-deficient diet for 8 months she still had some remaining yellow discoloration in the nasolabial folds and on the palms and soles. The results of an oral loading with beta-carotene (1 mg/kg) provide indirect evidence that the girl's carotenemia is due to a probably genetic defect in the metabolism of carotenoids.
我们描述了一名3岁女童，其皮肤长期发黄，血浆类胡萝卜素浓度比正常情况高出3倍，但无过量摄入胡萝卜素或家族性胡萝卜素血症病史。在给予8个月的缺胡萝卜素饮食后，她的鼻唇沟、手掌和脚底仍有一些残留的黄色色素沉着。口服β-胡萝卜素（1mg/kg）负荷试验的结果提供了间接证据，表明该女童的胡萝卜素血症可能是由于类胡萝卜素代谢的遗传缺陷所致。
