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恶性肿瘤食管切除术后的胃肠功能

Gastrointestinal function following esophagectomy for malignancy.

作者信息

Finley F J, Lamy A, Clifton J, Evans K G, Fradet G, Nelems B

机构信息

Department of Surgery, Vancouver Hospital, British Columbia, Canada.

出版信息

Am J Surg. 1995 May;169(5):471-5. doi: 10.1016/s0002-9610(99)80197-4.

Abstract

BACKGROUND

The frequency and causes of gastrointestinal complications following esophagectomy for malignancy are unknown.

PATIENTS AND METHODS

We reviewed 295 esophagectomies performed for malignancy between January 1980 and September 1994 in order to determine the frequency and causes of early and late gastrointestinal complications.

RESULTS

Compared to transhiatal and left thoracoabdominal esophagectomies, esophagectomies carried out through a right posterolateral thoracotomy with cervical esophagogastric anastomosis had a higher incidence of delayed gastric emptying (11%), pneumonia (26%), and hospital death (9%). The same operation had a higher incidence of gastroesophageal reflux (20%) and dysphagia requiring esophageal dilatation (53%). We found no independent effect of gastric drainage procedures, feeding jejunostomy, preoperative radiotherapy, pathology, or age on these outcomes. Women had no operative mortality, but a higher incidence of gastroesophageal reflux and diarrhea following esophagectomy.

CONCLUSIONS

Surgical techniques aimed at improving gastric emptying following esophagectomy for cancer should improve operative morbidity and mortality.

摘要

背景

恶性肿瘤食管切除术后胃肠道并发症的发生率及原因尚不清楚。

患者与方法

我们回顾了1980年1月至1994年9月间因恶性肿瘤行食管切除术的295例患者,以确定早期和晚期胃肠道并发症的发生率及原因。

结果

与经裂孔和左胸腹联合食管切除术相比,经右后外侧开胸行颈部食管胃吻合的食管切除术,胃排空延迟(11%)、肺炎(26%)及住院死亡率(9%)的发生率更高。同样的手术方式,胃食管反流(20%)及需要食管扩张的吞咽困难(53%)的发生率更高。我们发现胃引流术、空肠造瘘喂养、术前放疗、病理或年龄对这些结果无独立影响。女性无手术死亡,但食管切除术后胃食管反流和腹泻的发生率更高。

结论

旨在改善癌症食管切除术后胃排空的手术技术应能降低手术发病率和死亡率。

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