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术前腹腔镜辅助喂养空肠造口术在接受微创食管癌切除术的癌症患者中是安全有效的。

Pre-therapy laparoscopic feeding jejunostomy is safe and effective in patients undergoing minimally invasive esophagectomy for cancer.

机构信息

Department of Surgery, College of Medicine, University of Florida, Gainesville, FL 32610-0109, USA.

出版信息

J Gastrointest Surg. 2013 Aug;17(8):1352-8. doi: 10.1007/s11605-013-2231-4. Epub 2013 May 25.

Abstract

OBJECTIVE

Laparoscopic feeding jejunostomy is a safe and effective means of providing enteral nutrition in the preoperative phase to esophageal cancer patients.

DESIGN

This research is a retrospective case series.

SETTING

This study was conducted in a university tertiary care center.

PATIENTS

Between August 2007 and April 2012, 153 laparoscopic feeding jejunostomies were performed in patients 10 weeks prior to their definitive minimally invasive esophagectomy.

MAIN OUTCOME MEASURES

The outcome is measured based on the technique, safety, and feasibility of a laparoscopic feeding jejunostomy in the preoperative phase of esophageal cancer patients.

RESULTS

One hundred fifty-three patients underwent a laparoscopic feeding jejunostomy approximately 1 and 10 week(s) prior to the start of their neoadjuvant therapy and definitive minimally invasive esophagectomy, respectively. Median age was 63 years. Of the patients, 75 % were males and 25 % were females. One hundred twenty-seven patients had gastroesophageal junction adenocarcinoma and 26 had squamous cell carcinoma. All patients completed their neoadjuvant chemoradiation therapy. The median operative time was 65 min. We had no intraoperative complications, perforation, postoperative bowel necrosis, bowel torsion, herniation, intraperitoneal leak, or mortality as a result of the laparoscopic feeding jejunostomy. Four patients were noted to have superficial skin infection around the tube, and 11 patients required a tube exchange for dislodgment, clogging, and leaking around the tube. All patients progressed to their definitive surgical esophageal resection.

CONCLUSION

A laparoscopic feeding jejunostomy is technically feasible, safe, and can provide appropriate enteral nutrition in the preoperative phase of esophageal cancer patients.

摘要

目的

腹腔镜辅助置放空肠喂养管是食管癌患者术前接受肠内营养的一种安全有效的方法。

设计

本研究为回顾性病例系列研究。

地点

本研究在一所大学的三级医疗中心进行。

患者

2007 年 8 月至 2012 年 4 月,在接受新辅助微创食管切除术的 10 周前,153 例腹腔镜辅助空肠喂养管置放术在患者中进行。

主要观察指标

研究结果基于食管癌患者术前阶段腹腔镜辅助空肠喂养管置放术的技术、安全性和可行性。

结果

153 例患者分别在开始新辅助治疗和微创根治性食管切除术的前 1 周和 10 周进行了腹腔镜辅助空肠喂养管置放术。中位年龄为 63 岁。其中 75%为男性,25%为女性。127 例患者为胃食管交界处腺癌,26 例为鳞状细胞癌。所有患者均完成新辅助放化疗。中位手术时间为 65 分钟。我们没有术中并发症、穿孔、术后肠坏死、肠扭转、疝、腹腔内漏或因腹腔镜辅助空肠喂养管置放术而导致的死亡。4 例患者发现管周皮肤浅表感染,11 例患者因管周移位、堵塞和渗漏需要更换管。所有患者均进展至根治性食管切除术。

结论

腹腔镜辅助空肠喂养管置放术技术上可行、安全,并可在食管癌患者术前阶段提供适当的肠内营养。

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