尿黑酸是霍乱弧菌、一种生丝微菌属菌株以及科氏希瓦氏菌中黑色素合成的主要前体。
Homogentisic acid is the primary precursor of melanin synthesis in Vibrio cholerae, a Hyphomonas strain, and Shewanella colwelliana.
作者信息
Kotob S I, Coon S L, Quintero E J, Weiner R M
机构信息
Department of Microbiology, University of Maryland, College Park 20742, USA.
出版信息
Appl Environ Microbiol. 1995 Apr;61(4):1620-2. doi: 10.1128/aem.61.4.1620-1622.1995.
Abstract
The enzyme p-hydroxyphenylpyruvate hydroxylase (HPPH) is involved in pigmentation (pyomelanin) via homogentisic acid (HGA). Pyomelanin formation is correlated with HGA production and expression of HPPH in three disparate marine species: Vibrio cholerae, a Hyphomonas strain, and Shewanella colwelliana. Induction of pigmentation in V. cholerae 569B by nutrient limitation also correlated with production of HGA.
摘要
对羟基苯丙酮酸羟化酶（HPPH）通过尿黑酸（HGA）参与色素沉着（脓黑素）过程。在三种不同的海洋物种中，即霍乱弧菌、一种生丝微菌菌株和科氏希瓦氏菌，脓黑素的形成与HGA的产生以及HPPH的表达相关。营养限制诱导霍乱弧菌569B产生色素沉着也与HGA的产生相关。
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