镰状细胞贫血中的非创伤性脂肪栓塞综合征

Nontraumatic fat embolism syndrome in sickle cell anemia.

作者信息

Horton D P, Ferriero D M, Mentzer W C

机构信息

Division of Pediatric Cardiology, University of California San Francisco 94143-0870, USA.

出版信息

Pediatr Neurol. 1995 Jan;12(1):77-80. doi: 10.1016/0887-8994(94)00108-e.

DOI:10.1016/0887-8994(94)00108-e

PMID:7748367

Abstract

A 14-year-old girl with sickle cell disease and nephrotic syndrome developed bone pain, followed by pulmonary edema, seizures, coma, and bilateral flaccid paralysis. Fat embolism syndrome was diagnosed by cranial magnetic resonance imaging and an exchange transfusion was performed. Within 3 months, all symptoms had resolved. It is concluded that fat embolism syndrome must be considered as a possible cause of acute neurologic deterioration in patients with sickle cell anemia.

摘要

一名患有镰状细胞病和肾病综合征的14岁女孩出现骨痛，随后出现肺水肿、癫痫发作、昏迷和双侧弛缓性麻痹。通过头颅磁共振成像诊断为脂肪栓塞综合征，并进行了换血治疗。3个月内，所有症状均已缓解。结论是，脂肪栓塞综合征必须被视为镰状细胞性贫血患者急性神经功能恶化的可能原因。