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瑞士弯曲杆菌肠炎的风险因素。

Risk factors for Campylobacter enteritis in Switzerland.

作者信息

Schorr D, Schmid H, Rieder H L, Baumgartner A, Vorkauf H, Burnens A

出版信息

Zentralbl Hyg Umweltmed. 1994 Dec;196(4):327-37.

PMID:7748438
Abstract

From February to December 1991, 167 sporadic cases of Campylobacter enteritis in Switzerland and 282 controls were enrolled in a case-control study using self-administered questionnaires. In the multivariate matched analysis, travel abroad was identified as the most important risk factor for an infection with Campylobacter (adjusted odds ratio [OR] = 21.2, 95% confidence interval [CI]7.6-56.2). Having foreign citizenship also increased the risk (OR = 6.7, 95% CI 1.3-34.5). Among food items consumed within five days before onset of illness, consumption of poultry liver was shown to be a risk factor (OR = 5.7, 95% CI 1.4-22.8), while the consumption of curd or cottage cheese lowered the risk (OR = 0.5, 95% CI 0.3-0.9). The unmatched analysis confirmed travel abroad and the consumption of poultry liver as risk factors and the consumption of curd or cottage cheese as being protective, and, in addition, identified the consumption of poultry as a risk factor (OR = 2.0, 95% CI 1.1-3.3). The study showed the feasibility of using self-administered questionnaires for this type of analysis. The method is logistically simple and reduces the cost of case-control studies.

摘要

1991年2月至12月,瑞士的167例散发性弯曲杆菌肠炎病例和282名对照者参与了一项使用自行填写问卷的病例对照研究。在多变量匹配分析中,出国旅行被确定为感染弯曲杆菌的最重要风险因素(调整后的优势比[OR]=21.2,95%置信区间[CI]7.6-56.2)。拥有外国公民身份也会增加风险(OR=6.7,95%CI 1.3-34.5)。在发病前五天内食用的食物中,食用家禽肝脏被证明是一个风险因素(OR=5.7,95%CI 1.4-22.8),而食用凝乳或农家干酪则降低了风险(OR=0.5,95%CI 0.3-0.9)。非匹配分析证实出国旅行和食用家禽肝脏是风险因素,食用凝乳或农家干酪具有保护作用,此外,还确定食用家禽是一个风险因素(OR=2.0,95%CI 1.1-3.3)。该研究表明了使用自行填写问卷进行此类分析的可行性。该方法在逻辑上很简单,降低了病例对照研究的成本。

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