Maguire A, Rugg-Gunn A J
Department of Child Dental Health, Dental School, University of Newcastle upon Tyne, England.
Int J Paediatr Dent. 1994 Jun;4(2):93-9. doi: 10.1111/j.1365-263x.1994.tb00111.x.
The medication regimens of 243 children aged 1-16 years were analysed. The children were resident in five Districts in the Northern Region, England and were taking medication orally in liquid or syrup form for chronic disease. 39% of the children were under 5 years of age and 44% were aged 5-11 years, with slightly more males in most age groups. Epilepsy, chronic renal disease and cystic fibrosis were the most common medical problems for which the medicines were prescribed long-term. The duration of medication ranged between 3 months and 12 years; the average duration varied according to the disease and the type of medicine. Most of the anticonvulsants and vitamins had been used for 2 years or more, whereas most of the anti-asthmatic drugs were used for a period of up to a year only. Twenty six (39%) of the 67 different preparations used contained sugar, 19 (28%) were sugar-free, and the sweetening agent in the remainder varied according to how they were prescribed. Specificity of prescribing was the major determinant in the dispensing of either the sugar-containing or the sugar-free medicines.
对243名1至16岁儿童的药物治疗方案进行了分析。这些儿童居住在英格兰北部地区的五个区，因慢性病正在口服液体或糖浆形式的药物。39%的儿童年龄在5岁以下，44%的儿童年龄在5至11岁，大多数年龄组中男性略多。癫痫、慢性肾病和囊性纤维化是最常见的长期开药的医疗问题。用药时长在3个月至12年之间；平均时长因疾病和药物类型而异。大多数抗惊厥药和维生素已使用两年或更长时间，而大多数抗哮喘药仅使用长达一年的时间。所使用的67种不同制剂中，26种（39%）含糖，19种（28%）无糖，其余制剂中的甜味剂根据开药方式而有所不同。开药的特异性是含糖类或无糖类药物配药的主要决定因素。
