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1985年至1990年间肝切除术后腹腔内感染并发症的发生情况。

Occurrence of intraperitoneal septic complications after hepatic resections between 1985 and 1990.

作者信息

Matsumata T, Yanaga K, Shimada M, Shirabe K, Taketomi A, Sugimachi K

机构信息

Second Department of Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

出版信息

Surg Today. 1995;25(1):49-54. doi: 10.1007/BF00309385.

DOI:10.1007/BF00309385
PMID:7749290
Abstract

In this study, the risk factors related to intraperitoneal septic complications occurring after hepatectomy (IPSCH) as well as the effect of various perioperative variables on the outcome of IPSCH between 1985 and 1990 were analyzed. Twenty-one of 211 patients (10.0%) developed IPSCH. The findings in the patients with IPSCH were compared with those in 190 patients without IPSCH. The significant variables associated with the development of IPSCH included a high incidence of accompanying chronic renal failure (14.3% vs 2.1%), a larger blood loss during surgery (2,130 vs 1,340 ml) as well as a greater amount of intraoperative blood replacement (1,130 vs 570 ml), and a greater weight of the resected liver (367 vs 233 g). IPSCH occurred in 10 of 12 patients who had postoperative bile leakage. Eighteen patients (85.7%) with IPSCH were discharged from the hospital after non-operative management; however, the hospital death rate (14.3% vs 1.1%) was significantly higher in patients with IPSCH. This review suggests that the incidence of IPSCH has not decreased recently. Thus, to prevent IPSCH, at least following bile leakage, it is necessary to perform a careful division of the liver parenchyma followed by a bile leakage test, and when this complication occurs unexpectedly in patients who have a good functional reserve of the remnant liver, IPSCH can be effectively drained percutaneously under ultrasound guidance.

摘要

本研究分析了1985年至1990年间与肝切除术后发生的腹腔内感染性并发症(IPSCH)相关的危险因素,以及各种围手术期变量对IPSCH结局的影响。211例患者中有21例(10.0%)发生了IPSCH。将发生IPSCH的患者的结果与190例未发生IPSCH的患者的结果进行了比较。与IPSCH发生相关的显著变量包括慢性肾衰竭伴发率高(14.3%对2.1%)、手术中失血量更大(2130对1340ml)以及术中输血量更多(1130对570ml),以及切除肝脏的重量更大(367对233g)。12例术后发生胆漏的患者中有10例发生了IPSCH。18例(85.7%)发生IPSCH的患者在非手术治疗后出院;然而,IPSCH患者的医院死亡率(14.3%对1.1%)显著更高。本综述表明,IPSCH的发生率最近并未下降。因此,为预防IPSCH,至少在胆漏后,有必要仔细分离肝实质,随后进行胆漏试验,并且当这种并发症在残余肝功能储备良好的患者中意外发生时,可在超声引导下经皮有效引流IPSCH。

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本文引用的文献

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Possibility of hepatic resection in patients on maintenance hemodialysis.维持性血液透析患者行肝切除术的可能性。
Hepatogastroenterology. 1993 Jun;40(3):249-52.
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Open and closed suction drainage after hepatic resection.
Surg Today. 1993;23(10):871-4. doi: 10.1007/BF00311364.
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Effect of splenic sequestration of erythrocytes on splenic clearance function and susceptibility to septic peritonitis.红细胞的脾脏扣押对脾脏清除功能及脓毒性腹膜炎易感性的影响。
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Intraperitoneal septic complications after hepatectomy.肝切除术后腹腔感染性并发症
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Intestinal bacteria translocate into experimental intra-abdominal abscesses.肠道细菌易位至实验性腹腔脓肿中。
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Blood transfusion and infectious complications following colorectal cancer surgery.结直肠癌手术后的输血与感染并发症
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Primary hepatic malignancy: surgical management and determinants of survival.原发性肝癌:手术治疗与生存的决定因素
Surgery. 1989 Oct;106(4):740-8; discussion 748-9.
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Improved early results of elective hepatic resection for liver tumors. One hundred consecutive hepatectomies in cirrhotic and noncirrhotic patients.肝肿瘤选择性肝切除的早期结果改善。对肝硬化和非肝硬化患者连续进行100例肝切除术。
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