Lu C S, Liu H M
Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan R.O.C.
J Formos Med Assoc. 1994 Oct;93(10):879-81.
A 23-year-old female developed progressive cerebellar ataxia as the only presentation of multiple sclerosis for 6 years. Abnormal evoked potentials, an increased oligoclonal band of IgG-K in the cerebrospinal fluid and disseminated white matter lesions in magnetic resonance images (MRI) were compatible with a diagnosis of clinically definite multiple sclerosis. After cyclosporine treatment, the ataxia became stable without further deterioration. A follow-up MRI six months later did not reveal any active lesions. The importance of MRI in the confirmation of the clinical diagnosis and the evaluation of therapeutic effects in patients with atypical multiple sclerosis is emphasized.
一名23岁女性出现进行性小脑共济失调，作为多发性硬化症的唯一表现长达6年。异常诱发电位、脑脊液中IgG-K寡克隆带增加以及磁共振成像（MRI）显示的散在白质病变与临床确诊的多发性硬化症诊断相符。环孢素治疗后，共济失调病情稳定，未进一步恶化。6个月后的随访MRI未发现任何活动性病变。强调了MRI在非典型多发性硬化症患者临床诊断确认和治疗效果评估中的重要性。
