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持续侧方旋转疗法对肝移植患者肺部并发症的影响。

Effects of continuous lateral rotation therapy on pulmonary complications in liver transplant patients.

作者信息

Whiteman K, Nachtmann L, Kramer D, Sereika S, Bierman M

机构信息

University of Pittsburgh Medical Center, Pa., USA.

出版信息

Am J Crit Care. 1995 Mar;4(2):133-9.

PMID:7749445
Abstract

BACKGROUND

When liver transplant candidates and recipients suffer from pulmonary complications of immobility, the results can be life-threatening. Continuous lateral rotation therapy has been reported to decrease complications of immobility.

OBJECTIVES

To determine whether continuous lateral rotation therapy decreases the duration of mechanical ventilation, intensive care unit length of stay, incidence or resolution of atelectasis, incidence or onset time of lower respiratory tract infection and pneumonia.

METHODS

Sixty-nine subjects admitted to a liver transplant intensive care unit at a university teaching hospital were randomly assigned to continuous lateral rotation therapy or a stationary bed. All subjects were mechanically ventilated for 24 hours and had a Glasgow Coma Scale score of 11 or less upon admission to the study. Subjects were followed until out of bed, unable to rotate for 3 consecutive days, or transferred from the intensive care unit. Data and chest roentgenogram results were collected on admission and daily during the study. Sputum culture results were obtained if available as part of normal patient care.

RESULTS

Incidence of lower respiratory tract infection was significantly lower and length of time to occurrence of lower respiratory tract infection was significantly longer in the continuous lateral rotation therapy group than in the stationary bed group.

CONCLUSIONS

Although continuous lateral rotation therapy did not affect duration of mechanical ventilation, length of stay, or incidence of atelectasis, it was effective in decreasing the incidence of, and increasing onset time to, lower respiratory tract infection in the liver transplantation population.

摘要

背景

当肝移植候选者和接受者出现因活动受限导致的肺部并发症时,后果可能危及生命。据报道,持续侧方旋转疗法可减少活动受限引起的并发症。

目的

确定持续侧方旋转疗法是否能缩短机械通气时间、重症监护病房住院时间、肺不张的发生率或缓解情况、下呼吸道感染和肺炎的发生率或发病时间。

方法

一所大学教学医院肝移植重症监护病房收治的69名患者被随机分配至持续侧方旋转疗法组或固定床组。所有患者均接受24小时机械通气,且入组时格拉斯哥昏迷量表评分为11分或更低。对患者进行随访,直至其下床、连续3天无法翻身或转出重症监护病房。在入组时及研究期间每日收集数据和胸部X线检查结果。如有条件,作为常规患者护理的一部分获取痰培养结果。

结果

持续侧方旋转疗法组下呼吸道感染的发生率显著低于固定床组,且下呼吸道感染发生的时间显著长于固定床组。

结论

尽管持续侧方旋转疗法并未影响机械通气时间、住院时间或肺不张的发生率,但它在降低肝移植患者下呼吸道感染的发生率及延长其发病时间方面是有效的。

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