Phillips J K
Surgical Critical Care Unit, Hospital of the University of Pennsylvania, Philadelphia, USA.
Crit Care Nurs Clin North Am. 1999 Jun;11(2):233-47. doi: 10.1016/S0899-5885(18)30164-3.
Acute respiratory distress syndrome is a complex clinical syndrome of respiratory failure that presents a challenge to every critical care team. Since the first clear description by Ashbaugh et al more than 30 years ago, much has been learned about the pathophysiologic process that occurs within the lungs after they suffer either a direct or indirect injury. Unfortunately, little success has been achieved in improving outcomes; however, hope is on the horizon. Current research evaluating optimal ventilator management, ECMO, the use of inhaled nitric oxide, and other experimental management strategies will hopefully combine to produce improved outcomes.
急性呼吸窘迫综合征是一种呼吸衰竭的复杂临床综合征，对每个重症监护团队都是一项挑战。自30多年前阿什baugh等人首次明确描述以来，我们对肺部遭受直接或间接损伤后发生的病理生理过程已经有了很多了解。不幸的是，在改善预后方面成效甚微；不过，曙光就在眼前。目前评估最佳通气管理、体外膜肺氧合、吸入一氧化氮的使用及其他实验性管理策略的研究，有望共同带来更好的预后。
