Lin F J, Wong D, Chan-Yeung M
Department of Medicine, Vancouver General Hospital, University of British Columbia, Canada.
Ann Allergy Asthma Immunol. 1995 May;74(5):398-404.
A high prevalence of positive skin reaction is commonly seen in children with asthma. Very little information is available on the prevalence of immediate skin test reactivity in adult patients with asthma.
We performed allergen skin tests on 260 patients with asthma and 168 patients with red cedar asthma using a battery of 24 allergens. Immediate skin test reactivity was considered to be present if the subject reacted to at least one allergen.
Forty-eight percent of adult asthmatic patients had immediate skin test reactivity. Age, sex, and race were predictors of prevalence of immediate skin test reactivity. The number of allergens used for skin testing also determined the prevalence. More than half the patients who had immediate skin test reactivity reacted to house dust mite allergen.
There was a high proportion of immediate skin test reactivity in adult patients with asthma and half of them had positive skin reactions to house dust mite. As avoidance of house dust mites has been shown to be effective in patients with asthma, allergy evaluation should be included in the management of adult patients with asthma.
哮喘儿童中皮肤反应阳性的患病率普遍较高。关于成年哮喘患者即刻皮肤试验反应性的患病率，现有信息非常少。
我们使用一组24种变应原，对260例哮喘患者和168例红雪松哮喘患者进行了变应原皮肤试验。如果受试者对至少一种变应原产生反应，则认为存在即刻皮肤试验反应性。
48%的成年哮喘患者有即刻皮肤试验反应性。年龄、性别和种族是即刻皮肤试验反应性患病率的预测因素。用于皮肤试验的变应原数量也决定了患病率。超过一半有即刻皮肤试验反应性的患者对屋尘螨变应原产生反应。
成年哮喘患者中即刻皮肤试验反应性的比例很高，其中一半对屋尘螨有阳性皮肤反应。由于已证明避免接触屋尘螨对哮喘患者有效，因此成年哮喘患者的管理中应包括过敏评估。
