Lin J J, Chang M K, Lee C C, Tsao W L
Department of Neurology, Tri-Service General Hospital, Taipei, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1995 Feb;55(2):156-62.
Hemiballism-hemichorea, a well documented movement disorder, is not uncommon in the clinic. However, systematic analysis of the condition in ethnic Chinese on clinical grounds, is still inexplicably lacking.
This study focused on 23 Chinese patients with hemiballism-hemichorea in Taiwan. The general data, clinical pictures, blood biochemistries, past histories of systemic disease, neuroradiological imaging, methods of treatment, and prognoses of these patients were analyzed retrospectively.
The study revealed that ischemic stroke (44%) is the leading cause of this movement disorder, and the metabolic disorder (22%) is also one of the common etiologies of dyskinesia in Chinese patients. In addition to those patients whose condition was caused by non-ketotic hyperglycemia, blood sugar had also obviously increased in patients where the cause was infarction. Pathological lesions contributed to hyperkinesia were found not only in the contralateral basal ganglion but also in the thalamus and subcortical areas. The characteristics of those patients where the cause was infarction and non-ketotic hyperglycemia were: age at onset greater than 60 years, and predominantly in women. Etiologies contributing to this movement disorder in younger patients differ from those in the older. Prognosis of the movement disorder in this study was favorable.
Hemiballism-hemichorea is predisposed to occur in older Chinese women, and metabolic disorder is an important etiology of the movement disorder. When the dyskinesia is encountered in the clinic, the metabolic disorders must be first ruled out as the problem may be rapidly resolved by achieving metabolic control.
偏身投掷症-偏身舞蹈症是一种有充分文献记载的运动障碍，在临床上并不少见。然而，基于临床原因对中国汉族人群中该病症的系统分析仍莫名缺失。
本研究聚焦于台湾地区23例偏身投掷症-偏身舞蹈症的中国患者。对这些患者的一般资料、临床表现、血液生化指标、全身疾病既往史、神经放射影像学、治疗方法及预后进行回顾性分析。
研究显示，缺血性中风（44%）是这种运动障碍的主要病因，代谢紊乱（22%）也是中国患者运动障碍的常见病因之一。除了那些由非酮症高血糖引起的患者外，梗死导致的患者血糖也明显升高。发现导致运动过多的病理损害不仅存在于对侧基底神经节，还存在于丘脑和皮质下区域。梗死和非酮症高血糖导致的患者特征为：发病年龄大于60岁，且以女性为主。年轻患者中导致这种运动障碍的病因与老年患者不同。本研究中运动障碍的预后良好。
偏身投掷症-偏身舞蹈症易发生于中国老年女性，代谢紊乱是运动障碍的重要病因。临床遇到运动障碍时，必须首先排除代谢紊乱，因为通过实现代谢控制问题可能会迅速得到解决。
