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生理心率变化对正常胎儿左心室大小及二尖瓣血流速度的影响

Effect of physiological heart rate changes on left ventricular dimensions and mitral blood flow velocities in the normal fetus.

作者信息

Tsyvian P B, Malkin K V, Wladimiroff J W

机构信息

Biophysical Laboratory, Mother and Child Care Institute, Yekaterinburg, Russian Federation.

出版信息

Early Hum Dev. 1995 Jan 30;40(2):109-14. doi: 10.1016/0378-3782(94)01595-G.

DOI:10.1016/0378-3782(94)01595-G
PMID:7750438
Abstract

M-mode echo recordings of the left ventricle (LV) and inflow LV Doppler velocimetry were performed in nine normal fetuses at a gestational age of 36-39 weeks. In each fetus approximately 80 consecutive cardiac cycles were digitized. The duration of each cardiac cycle (T) and the corresponding end-diastolic (EDD), end-systolic (ESD) dimensions of LV or the peak velocity of early (E) and late atrial (A) mitral flow parameters was calculated. The role of sonographic parameters on current (Tn) and preceding (Tn-1) cardiac cycles was assessed using linear regression. Significant dependency of ventricular EDD and transmitral A peak velocity upon Tn was demonstrated. We speculate that atrial systole has an important role to play in the beat-to-beat regulation of fetal stroke volume.

摘要

对9例孕龄为36 - 39周的正常胎儿进行了左心室M型超声心动图记录及左心室流入道多普勒流速测定。对每个胎儿大约连续80个心动周期进行数字化处理。计算每个心动周期的持续时间(T)以及相应的左心室舒张末期内径(EDD)、收缩末期内径(ESD),或二尖瓣血流参数中早期(E)和晚期心房(A)峰值流速。使用线性回归评估超声参数对当前心动周期(Tn)和前一个心动周期(Tn-1)的作用。结果表明心室EDD和二尖瓣A峰值流速对Tn有显著依赖性。我们推测心房收缩在胎儿每搏输出量的逐搏调节中起重要作用。

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