O'Callaghan M J, Burns Y, Gray P, Harvey J M, Mohay H I, Rogers Y, Tudehope D I
Mater Misericordiae Public Hospitals, Brisbane, Queensland, Australia.
Early Hum Dev. 1995 Jan 30;40(2):115-28. doi: 10.1016/0378-3782(94)01597-I.
A 2-year cohort of 63 surviving extremely low birth weight (ELBW) infants was prospectively studied and 60 of these infants, together with 44 normal birth weight control infants, were assessed at 2 years of age for intellectual abilities, motor skills, growth and health. The total ELBW group differed significantly from controls on overall Griffiths developmental quotient (99.3 vs. 103.8 P = 0.02) and in the personal/social subscale (100.7 vs. 106.7 P = 0.01). A subset of 43 of the ELBW infants was identified as low risk at discharge. No statistically significant differences were present between the low risk ELBW subset and controls in intellectual abilities though both the total ELBW group and the low risk ELBW subset differed from controls in fine and gross motor abilities, and in weight at 2 years. The total ELBW group also experienced more frequent ill health and hospital readmission.
对63名存活的极低出生体重(ELBW)婴儿进行了为期2年的前瞻性研究,并在这些婴儿2岁时,对其中60名婴儿以及44名正常出生体重的对照婴儿的智力、运动技能、生长和健康状况进行了评估。ELBW组在总体格里菲斯发育商数(99.3对103.8,P = 0.02)和个人/社会分量表(100.7对106.7,P = 0.01)方面与对照组有显著差异。43名ELBW婴儿在出院时被确定为低风险。低风险ELBW亚组与对照组在智力方面没有统计学上的显著差异,不过ELBW组和低风险ELBW亚组在精细和粗大运动能力以及2岁时的体重方面与对照组存在差异。ELBW组还经历了更频繁的健康问题和再次入院情况。